Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | IARS1 | P41252 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736585 | 0.88 | ALDH1A1 (0.53) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL349587 | 0.85 | GAA (0.67) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL8736645 | 0.81 | GAA (0.76) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL10513612 | 0.78 | GAA (0.71) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL30388881 | 0.78 | GAA (0.75) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL29699330 | 0.78 | GAA (1.00) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL18255551 | 0.78 | GAA (0.75) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL347877 | 0.78 | GAA (1.00) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL490506 | 0.77 | ALOX15 (0.60) | GAATSHRNFKB1CYP1A2CYP3A4 | |
| SCHEMBL491225 | 0.77 | CYP19A1 (0.60) | GAATSHRNFKB1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696566-B1 | Process for production of phenyllactic acid derivative | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5684186-A | HYDROGENATION OF A PHENYLPYRUVIC DERIVATIVE | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0696566-A1 | Process for production of phenyllactic acid derivative | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |