Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286320 | 0.92 | LMNA (0.65) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL10044854 | 0.91 | LMNA (0.56) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL9389982 | 0.89 | LMNA (0.61) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL9316969 | 0.88 | LMNA (0.60) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL8906487 | 0.88 | LMNA (0.60) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL10044835 | 0.88 | LMNA (0.54) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL10044853 | 0.87 | LMNA (0.69) | LMNACYP2C19HIF1A | |
| SCHEMBL9451103 | 0.87 | LMNA (0.59) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL9352729 | 0.87 | LMNA (0.59) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 | |
| SCHEMBL22662268 | 0.85 | LMNA (0.57) | LMNACYP2C19HIF1AMAP2K1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
| US-20090053142-A1 | CONTRAST AGENTS | WYNN DUNCAN | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090053142-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | LMNA 2151/4885CYP2C19 4077/4885HIF1A 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.