Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18488199 | 0.85 | MAPT (0.78) | MAPTKMT2AGAANPSR1POLB | |
| SCHEMBL13369044 | 0.79 | PPARA (0.45) | MAPTKMT2AGAANPSR1POLB | |
| SCHEMBL18334271 | 0.74 | MAPT (0.71) | MAPTKMT2AGAANPSR1POLB | |
| SCHEMBL20434657 | 0.74 | MAPT (0.84) | MAPTKMT2AGAANPSR1POLB | |
| SCHEMBL18317471 | 0.73 | MAPT (1.00) | MAPTKMT2AGAANPSR1POLB | |
| Mahanimbine SCHEMBL18488200 | 0.71 | MAPT (1.00) | MAPTKMT2AGAANPSR1POLB | |
| Mahanimbine SCHEMBL18488203 | 0.71 | MAPT (1.00) | MAPTKMT2AGAANPSR1POLB | |
| Mahanimbine SCHEMBL2991765 | 0.71 | MAPT (1.00) | MAPTKMT2AGAANPSR1POLB | |
| SCHEMBL31723092 | 0.69 | MAPT (0.73) | MAPTKMT2AGAANPSR1POLB | |
| Atractylochromene SCHEMBL2991263 | 0.67 | ALOX5 (1.00) | MAPTKMT2AGAANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | GEORGETOWN UNIVERSITY (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2323982-B1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | UNIV GEORGETOWN (US) | 2012-02-29 | — | — | EP | disclosed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| US-20100130579-A1 | CANCER THERAPY | GEORGETOWN UNIVERSITY (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2008051523-A2 | CARBAZOLE DERIVATIVES USEFUL AS MEDICAMENTS IN CANCER THERAPY | GEORGETOWN UNIVERSITY (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | RASSF5, RASSF2, MKI67 | MAPT 4658/4885KMT2A 454/4885GAA 4044/4885 |
| US-20100130579-A1 | CANCER THERAPY | RASSF5, RASSF2, DNMT1 | MAPT 3975/4885KMT2A 37/4885GAA 4202/4885 |
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | RASSF5, RASSF2, MKI67 | MAPT 4658/4885KMT2A 454/4885GAA 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.