Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24092180 | 0.80 | CYP2C19 (0.47) | CYP2C19TAAR1HTR2ALMNAHRH1 | |
| SCHEMBL23531275 | 0.79 | RIPK1 (0.34) | CYP2D6CYP2C19KMT2ATAAR1HTR2A | |
| SCHEMBL23531297 | 0.78 | CYP2D6 (0.34) | CYP2D6CYP2C19TAAR1HTR2ASLC6A3 | |
| SCHEMBL1894870 | 0.78 | SMN1; SMN2 (0.39) | CYP2D6CYP2C19KMT2ALMNAKDM4E | |
| SCHEMBL1889809 | 0.75 | MAPT (0.43) | KMT2ALMNASLC6A3TDP1L3MBTL1 | |
| SCHEMBL13654815 | 0.74 | LMNA (0.48) | KMT2ATAAR1HTR2ALMNAHRH1 | |
| SCHEMBL68782 | 0.73 | HTR2A (0.46) | CYP2D6CYP2C19TAAR1HTR2AHRH1 | |
| SCHEMBL11479295 | 0.73 | SOAT1 (0.40) | HTR2ATDP1 | |
| SCHEMBL7239847 | 0.72 | TAAR1 (0.52) | CYP2D6CYP2C19TAAR1HTR2AHRH1 | |
| SCHEMBL14191123 | 0.72 | TAAR1 (0.52) | CYP2D6TAAR1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101803-B2 | Process for the addition of thiolates to α,β-unsaturated carbonyl or sulfonyl compounds | DOW AGROSCIENCES LLC (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100048939-A1 | PROCESS FOR THE ADDITION OF THIOLATES TO ?,?-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048939-A1 | PROCESS FOR THE ADDITION OF THIOLATES TO ?,?-UNSATURATED CARBONYL OR SULFONYL COMPOUNDS | CBS, TST, KCNJ1 | CYP2D6 2487/4885CYP2C19 3374/4885KMT2A 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.