Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438876 | 0.91 | HPGD (0.43) | MAPTHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL7219667 | 0.80 | ALDH1A1 (0.54) | MAPTHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8619629 | 0.80 | MAPK1 (0.60) | MAPTHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL10046434 | 0.79 | SMN1; SMN2 (0.58) | MAPTHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4263785 | 0.79 | ALDH1A1 (0.61) | MAPTHPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL12408064 | 0.77 | MAPT (0.51) | MAPTHPGDSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3438878 | 0.77 | CETP (0.58) | MAPTALDH1A1RAB9APOLBLMNA | |
| SCHEMBL13063142 | 0.76 | MAPK1 (0.53) | MAPTSMN1; SMN2HTTALDH1A1RAB9A | |
| SCHEMBL17444748 | 0.75 | PARP14 (0.63) | MAPTHPGDSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL10436820 | 0.74 | HDAC3 (0.64) | MAPTHPGDHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077990-A1 | Alkene Aziridination | NATIONAL SCIENCE FOUNDATION | 2012-03-29 | — | — | US | disclosed |
| US-20120077990-A1 | Alkene Aziridination | NATIONAL SCIENCE FOUNDATION | 2012-03-29 | — | — | US | disclosed |
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | PPOX, POR, PCCA | MAPT 3289/4885HPGD 576/4885SMN1; SMN2 3724/4885 |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | MAPT 3785/4885HPGD 1140/4885SMN1; SMN2 3875/4885 |
| US-20120077990-A1 | Alkene Aziridination | AZI2, PPOX, GLI2 | MAPT 4635/4885HPGD 3026/4885SMN1; SMN2 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.