⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313282 | 0.82 | — | — | |
| SCHEMBL11987407 | 0.79 | — | — | |
| SCHEMBL24796620 | 0.74 | PTPN1 (0.32) | — | |
| SCHEMBL441723 | 0.73 | — | — | |
| SCHEMBL24312513 | 0.71 | — | — | |
| SCHEMBL893868 | 0.71 | — | — | |
| SCHEMBL20086666 | 0.71 | APLNR (0.37) | — | |
| SCHEMBL7755872 | 0.71 | HTR7 (0.42) | — | |
| SCHEMBL20630755 | 0.69 | — | — | |
| SCHEMBL18227494 | 0.69 | HTR7 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| EP-4225447-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076625-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-1918778-B1 | Compositions and processes for immersion lithography | ROHM & HAAS ELECT MAT (US) | 2016-08-03 | — | — | EP | disclosed |
| US-9244355-B2 | Compositions and processes for immersion lithography | ROHM AND HAAS ELECTRONIC MATERIALS, LLC (US) | 2016-01-26 | — | — | US | disclosed |
| US-9244355-B2 | Compositions and processes for immersion lithography | ROHM AND HAAS ELECTRONIC MATERIALS, LLC (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150057452-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | CATYLIX, INC. (US) | 2015-02-26 | — | — | US | disclosed |
| EP-2420891-A1 | Compositions and processes for immersion lithography | Rohm and Haas Electronic Materials LLC (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20080193872-A1 | Applying on photoresist, a photoactive component, and material(s) having a water contact angle changeable by base treatment; activation by immersion exposing to radiation; reduced leaching; pentafluoroacrylate-ethyl cyclopentyl methacrylate-trimethylolpropane triacrylate terpolymer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080193872-A1 | Applying on photoresist, a photoactive component, and material(s) having a water contact angle changeable by base treatment; activation by immersion exposing to radiation; reduced leaching; pentafluoroacrylate-ethyl cyclopentyl methacrylate-trimethylolpropane triacrylate terpolymer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-08-14 | — | — | US | disclosed |