Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.54 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.54 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160263 | 0.86 | KMT2A (0.68) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL4408732 | 0.84 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL12445012 | 0.81 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL16312144 | 0.80 | SLC16A3 (0.70) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL10046608 | 0.77 | ALDH1A1 (0.69) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL15297121 | 0.76 | SMN1; SMN2 (0.45) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL16312152 | 0.75 | ALDH1A1 (0.71) | MEN1KMT2ASMN1; SMN2LMNATNNI3 | |
| SCHEMBL26552256 | 0.75 | GABRA1 (0.51) | LMNAMAPTRAB9AGABRA1GABRG2 | |
| SCHEMBL159816 | 0.73 | ALDH1A1 (0.58) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL31539850 | 0.72 | MEN1 (0.97) | MEN1KMT2ASMN1; SMN2LMNATNNI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2126625-B1 | SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE | NITTO DENKO CORP (JP) | 2012-02-22 | — | — | EP | disclosed |