Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312152 | 0.98 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL255364 | 0.83 | MEN1 (0.97) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL255365 | 0.83 | MEN1 (0.97) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14571074 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL32675887 | 0.81 | MEN1 (1.00) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13710832 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL141719 | 0.77 | MAPT (0.63) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15138675 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL140748 | 0.77 | MAPT (0.63) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10046803 | 0.77 | MEN1 (0.54) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573888-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160168083-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-06-16 | — | — | US | disclosed |
| US-9296728-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296728-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140371272-A1 | THERAPEUTIC COMPOUNDS | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2014-12-18 | — | — | US | disclosed |
| EP-2126625-B1 | SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE | NITTO DENKO CORP (JP) | 2012-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371272-A1 | THERAPEUTIC COMPOUNDS | HLA-DRB1, SLC10A1, NFATC1 | ALDH1A1 266/4885MAPT 3241/4885MEN1 28/4885 |
| US-20160168083-A1 | THERAPEUTIC COMPOUNDS | HLA-DRB1, SLC10A1, NFATC1 | ALDH1A1 359/4885MAPT 3327/4885MEN1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.