Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368344 | 0.81 | LMNA (0.48) | LMNANFE2L2PTGS1PTGS2GRIN2D | |
| SCHEMBL26552230 | 0.78 | TRPA1 (0.46) | GABRA1GABRG2GABRB3LMNANFE2L2 | |
| SCHEMBL30980828 | 0.75 | EGFR (0.53) | LMNA | |
| SCHEMBL1790273 | 0.75 | EGFR (0.53) | LMNA | |
| SCHEMBL1793712 | 0.75 | EGFR (0.53) | LMNA | |
| SCHEMBL10046803 | 0.75 | MEN1 (0.54) | GABRA1GABRG2GABRB3LMNAPOLB | |
| SCHEMBL26552234 | 0.73 | ALDH1A1 (0.53) | GABRA1GABRG2GABRB3LMNAPOLB | |
| SCHEMBL3538900 | 0.73 | NFE2L2 (0.43) | LMNANFE2L2PTGS1PTGS2GRIN2D | |
| SCHEMBL3538902 | 0.73 | NFE2L2 (0.43) | LMNANFE2L2PTGS1PTGS2GRIN2D | |
| SCHEMBL12826361 | 0.73 | NFE2L2 (0.43) | LMNANFE2L2PTGS1PTGS2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | GABRA1 3526/4885GABRG2 2689/4885GABRB3 1610/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | GABRA1 3526/4885GABRG2 2689/4885GABRB3 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.