Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635377 | 0.87 | PSMB8 (0.65) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL21682157 | 0.83 | PSMB8 (0.69) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL31123708 | 0.83 | PSMB8 (0.69) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2754297 | 0.80 | PSMB8 (0.70) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2128591 | 0.80 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL29572038 | 0.80 | PSMB8 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL2711265 | 0.80 | PSMB8 (0.75) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL12344738 | 0.79 | ALDH1A1 (0.60) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL329577 | 0.78 | PSMB8 (0.72) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL29164335 | 0.78 | PSMB8 (1.00) | PSMB8PSMB5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036832-B1 | VULCANIZATION OF RUBBER WITH 2-(ALKYLSULFINYL)-BENZOTHIAZOLES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-06-18 | — | — | EP | claimed |
| US-4350818-A | CATALYTIC ALKYLATION OF 2-MERCAPTOBENXOTHIAZOLE FOLLOWED BY OXIDATION WITH HYPOCHLORITE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-21 | — | — | US | claimed |
| EP-0036832-A1 | Vulcanization of rubber with 2-(alkylsulfinyl)-benzothiazoles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-09-30 | — | — | EP | claimed |
| US-20230374060-A1 | NOVEL METHOD FOR PREPARING INOTODIOL | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2023-11-23 | — | — | US | disclosed |
| EP-4130020-A1 | NOVEL METHOD FOR PREPARING INOTODIOL | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-02-08 | — | — | EP | disclosed |
| US-8895696-B1 | Methods for forming peptides and peptide conjugates and peptides and peptide conjugates compositions formed thereby | THE UNIVERSITY OF TOLEDO (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895734-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-11-25 | — | — | US | disclosed |
| US-8884008-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-11-11 | — | — | US | disclosed |
| US-20140323728-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2014-10-30 | — | — | US | disclosed |
| US-8859766-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-10-14 | — | — | US | disclosed |
| US-20140155604-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2014-06-05 | — | — | US | disclosed |
| US-20140155605-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2014-06-05 | — | — | US | disclosed |
| US-8680253-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-03-25 | — | — | US | disclosed |
| US-20120040918-A9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2012-02-16 | — | — | US | disclosed |
| US-20110178031-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2011-07-21 | — | — | US | disclosed |
| EP-0036832-B1 | VULCANIZATION OF RUBBER WITH 2-(ALKYLSULFINYL)-BENZOTHIAZOLES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4350818-A | CATALYTIC ALKYLATION OF 2-MERCAPTOBENXOTHIAZOLE FOLLOWED BY OXIDATION WITH HYPOCHLORITE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0036832-A1 | Vulcanization of rubber with 2-(alkylsulfinyl)-benzothiazoles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4280967-A | Vulcanization of rubber with 2-(alkylsulfinyl)-benzothiazoles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374060-A1 | NOVEL METHOD FOR PREPARING INOTODIOL | ITPA, INO80C, INO80 | PSMB8 1940/4885PSMB5 2021/4885CA12 4169/4885 |
| US-20140323728-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | PSMB8 4182/4885PSMB5 4437/4885CA12 2609/4885 |
| US-20140155605-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | PSMB8 4182/4885PSMB5 4437/4885CA12 2609/4885 |
| US-20120040918-A9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | PSMB8 4182/4885PSMB5 4437/4885CA12 2609/4885 |
| US-20110178031-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | PSMB8 4182/4885PSMB5 4437/4885CA12 2609/4885 |
| US-20140155604-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | PSMB8 4182/4885PSMB5 4437/4885CA12 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.