Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741541 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL31246157 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL19007853 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL14959576 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL20793265 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL30884891 | 0.86 | SLC15A1 (0.49) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL7365728 | 0.85 | SLC15A1 (0.57) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL111390 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 | |
| SCHEMBL7140669 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1SLC15A1TDP1 | |
| SCHEMBL7406398 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1SLC15A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791162-B2 | Cathepsin cysteine protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010161-A1 | NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP | ABCB1, ABCB11, ABCC1 | ALDH1A1 2049/4885MAPK1 2470/4885L3MBTL1 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.