SCHEMBL10048010

SCHEMBL10048010

C1=Cc2c(n(-c3cccc(-c4cccc(-c5ccccc5-c5cccc6cccnc56)n4)n3)c3ccccc23)CN1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13892617 0.91 METAP2 (0.30) CNR2
SCHEMBL9267421 0.89 MAPK14 (0.35)
SCHEMBL4562423 0.87
SCHEMBL9922052 0.84 MAP4K1 (0.31) CNR2
SCHEMBL4562077 0.82 NISCH (0.33)
SCHEMBL4561489 0.82 KDM4E (0.34) CNR2
SCHEMBL5944264 0.80 CNR2 (0.35) CNR2
SCHEMBL10047771 0.79 TUBB4A (0.30)
SCHEMBL10048246 0.77 MEN1 (0.31)
SCHEMBL9261877 0.76 TUBB4A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053051-B1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2012-05-02 EP disclosed
EP-2053051-A1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE HAVING SUBSTITUTED PYRIDYL GROUP ATTACHED THERETO, AND ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2009-04-29 EP disclosed