Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.30 |
| ▸ | AKT2 | P31751 | 2/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892617 | 0.88 | METAP2 (0.30) | CNR2 | |
| SCHEMBL10048010 | 0.84 | CNR2 (0.31) | CNR2 | |
| SCHEMBL16016346 | 0.81 | HTR1A (0.33) | — | |
| SCHEMBL16016433 | 0.80 | CYP11B1 (0.32) | — | |
| SCHEMBL4561489 | 0.79 | KDM4E (0.34) | CNR2 | |
| SCHEMBL4562423 | 0.78 | — | — | |
| SCHEMBL9267421 | 0.77 | MAPK14 (0.35) | — | |
| SCHEMBL18199763 | 0.76 | KDM4E (0.34) | — | |
| SCHEMBL12919175 | 0.76 | IKBKE (0.34) | ACVRL1ACVR1CNR2AKT1AKT2 | |
| SCHEMBL13892803 | 0.76 | MAOA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463288-A1 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | Hodogaya Chemical Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |