Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797190 | 0.91 | ELANE (0.52) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL15281144 | 0.89 | ELANE (0.58) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL18463551 | 0.89 | PDK2 (0.56) | ELANEPGRPDK2TDP1ALDH1A1 | |
| SCHEMBL13191327 | 0.85 | ELANE (0.62) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL29522682 | 0.84 | MEN1 (0.52) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL12997894 | 0.84 | MEN1 (0.52) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL1855552 | 0.84 | MEN1 (0.52) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL12997896 | 0.84 | MEN1 (0.52) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL12685770 | 0.83 | ELANE (0.55) | ELANEPGRPDK2MAOAMAOB | |
| SCHEMBL14702110 | 0.82 | PDK2 (0.42) | ELANEPGRPDK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20220140249-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2022-05-05 | — | — | US | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-9029425-B2 | Substituted dibenzo[FG,OP]tetracenes and formulations or electronic devices containing the same | MERCK PATENT GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-20150057445-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-20150057445-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| US-8906893-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-8906893-B2 | Substituted tetraarylbenzenes | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| WO-2012038029-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220140249-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CDYL, MRPL38, CDYL2 | ELANE 2036/4885PGR 1867/4885PDK2 3992/4885 |
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | ELANE 1010/4885PGR 1812/4885PDK2 741/4885 |
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | ELANE 1010/4885PGR 1812/4885PDK2 741/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | ELANE 1010/4885PGR 1812/4885PDK2 741/4885 |
| US-20160308146-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | ELANE 1010/4885PGR 1812/4885PDK2 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.