SCHEMBL18463551

SCHEMBL18463551

Cc1ccc2c(c1)C(C)(C)c1ccccc1-2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.56
ELANE P08246 1/20 0.45
PGR P06401 1/20 0.44
NPSR1 Q6W5P4 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MDM2 Q00987 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MLNR O43193 1/20 0.39
NR1I2 O75469 1/20 0.39
CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4368315 0.89 PDK2 (0.46) PDK2ELANENPSR1TDP1CASP3
SCHEMBL10048314 0.89 ELANE (0.58) PDK2ELANEPGRNPSR1TDP1
SCHEMBL13367505 0.88 PDK2 (0.46) PDK2ELANEPGRNPSR1TDP1
SCHEMBL19085025 0.88 PDK2 (0.61) PDK2ELANEPGRNPSR1TDP1
SCHEMBL25629567 0.86 PDK2 (0.51) PDK2ELANEPGRNPSR1TDP1
SCHEMBL17742479 0.84 PDK2 (0.43) PDK2ELANEPGRNPSR1TDP1
SCHEMBL5014621 0.82 HTR2A (0.43) PDK2PGRTDP1LMNAKDM4E
SCHEMBL5062909 0.82 HTR2A (0.43) PDK2PGRTDP1LMNAKDM4E
SCHEMBL25785799 0.82 PDK2 (0.62) PDK2PGRNPSR1RAB9ALMNA
SCHEMBL283246 0.82 HTR2A (0.48) PDK2PGRTDP1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
EP-4113643-B1 SPIRO[FLUORENE-9,9'-(THIO)XANTHENE] COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-09 EP disclosed
US-20230212335-A1 Polymeric Compound, Electroluminescent Device Material, Electroluminescent Device, and Electronic Device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-06 US disclosed
US-11312717-B2 Organic nano-grid, nano-polymer thereof and preparation method therefor NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) 2022-04-26 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11183417-B2 Method for manufacturing laminate and method for manufacturing substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-11-23 US disclosed
US-20210163482-A1 ORGANIC NANO-GRID, NANO-POLYMER THEREOF AND PREPARATION METHOD THEREFOR NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS (CN) 2021-06-03 US disclosed
EP-3674343-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-01 EP disclosed
EP-3347354-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-06-17 EP disclosed
US-20200144093-A1 METHOD FOR MANUFACTURING LAMINATE AND METHOD FOR MANUFACTURING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-07 US disclosed
US-20180107115-A1 FILM MATERIAL AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-04-19 US disclosed
US-9934996-B2 Wafer processing bonding arrangement, wafer laminate, and thin wafer manufacturing method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-04-03 US disclosed
US-9890254-B2 Resin composition, resin film, and semiconductor device and method for manufacturing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-13 US disclosed
EP-3242343-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HAVING RGB PIXEL AREAS Beijing Visionox Technology Co., Ltd. (CN) 2017-11-08 EP disclosed
US-20170253795-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-07 US disclosed
EP-3214104-A1 CYANIC ACID ESTER COMPOUND, METHOD FOR PRODUCING SAME, RESIN COMPOSITION AND CURED PRODUCT Mitsubishi Gas Chemical Company, Inc. (JP) 2017-09-06 EP disclosed
EP-3187522-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company Limited (JP) 2017-07-05 EP disclosed
US-9620429-B2 Semiconductor apparatus, stacked semiconductor apparatus, encapsulated stacked-semiconductor apparatus, and method for manufacturing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US disclosed
US-20170053821-A1 WAFER PROCESSING BONDING ARRANGEMENT, WAFER LAMINATE, AND THIN WAFER MANUFACTURING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
WO-2017016630-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PDK2 3023/4885ELANE 3715/4885PGR 3716/4885
US-11312717-B2 Organic nano-grid, nano-polymer thereof and preparation method therefor ITGB2, CD81, ITGAV PDK2 961/4885ELANE 4519/4885PGR 2035/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 PDK2 2530/4885ELANE 3136/4885PGR 2025/4885
US-20210163482-A1 ORGANIC NANO-GRID, NANO-POLYMER THEREOF AND PREPARATION METHOD THEREFOR WASF2, CYP4F11, ITGAV PDK2 1068/4885ELANE 4640/4885PGR 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.