SCHEMBL1004853

SCHEMBL1004853

Cc1cc(C)c(C(=O)N(C)C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MCOLN3 Q8TDD5 1/20 0.46
HTT P42858 1/20 0.41
TAS1R3 Q7RTX0 3/20 0.39
TAS1R1 Q7RTX1 3/20 0.39
TAS1R2 Q8TE23 3/20 0.39
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
GFER P55789 1/20 0.38
GAA P10253 1/20 0.38
NPC1 O15118 1/20 0.37
MAPK1 P28482 1/20 0.36
TPMT P51580 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16463845 0.79 KMT2A (0.36) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL4047990 0.76 CYP19A1 (0.43) HPGDKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL1003974 0.76 KDM4E (0.42) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL1003369 0.76 HPGD (0.69) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL1002896 0.76 CRHR1 (0.48) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL1004408 0.74 HPGD (0.45) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL22109937 0.74 HPGD (0.47) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL6666412 0.74 HPGD (0.52) HPGDKMT2ASMN1; SMN2MEN1LMNA
SCHEMBL1006734 0.73 TPMT (0.54) HPGDSMN1; SMN2ALDH1A1TPMT
SCHEMBL5243011 0.73 KDM4E (0.63) HPGDKMT2ASMN1; SMN2MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012885-A Preheating-free welded steel plate and production method thereof, and preheating-free welding method 江苏沙钢钢铁有限公司 2026-05-12 CN claimed
CN-119039906-A Emulsion binder for low-odor glass fiber chopped strand mats and preparation method thereof 泰山玻璃纤维有限公司 2024-11-29 CN claimed
CN-122012885-A Preheating-free welded steel plate and production method thereof, and preheating-free welding method 江苏沙钢钢铁有限公司 2026-05-12 CN disclosed
US-12442027-B2 Method of reducing aromatic nitro compounds AMGEN INC. (US) 2025-10-14 US disclosed
EP-3354730-B1 LINALOOL PRODUCTION METHOD AJINOMOTO KK (JP) 2025-06-18 EP disclosed
CN-120014999-A Guqin music evaluation standard system and playing style library construction method 广州熹道文化传播有限公司 2025-05-16 CN disclosed
CN-119502867-B Time synchronization method applied to electromechanical braking system and braking system 苏州利氪科技有限公司 2025-05-16 CN disclosed
CN-119502867-A Time synchronization method applied to electromechanical braking system and braking system 苏州利氪科技有限公司 2025-02-25 CN disclosed
US-12162816-B2 Method of reducing aromatic nitro compounds JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2024-12-10 US disclosed
CN-119039906-A Emulsion binder for low-odor glass fiber chopped strand mats and preparation method thereof 泰山玻璃纤维有限公司 2024-11-29 CN disclosed
CN-118453860-A Nanoparticle for colorectal cancer chemotherapy-photothermal synergistic treatment and preparation method and application thereof 上海市第十人民医院 2024-08-09 CN disclosed
CN-108138168-B Linalool composition and preparation method thereof 味之素株式会社 2022-04-05 CN disclosed
CN-111278869-B Resin composition 纳美仕有限公司 2022-02-11 CN disclosed
CN-103459434-B Hydrosilylation of vinyl macromers using metallocenes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-05-11 CN disclosed
CN-105017058-A 2,4,6,N,N-pentamethylbenzamide preparation method INSIGHT HIGH TECHNOLOGY JIANGSU CO LTD 2015-11-04 CN disclosed
CN-105017058-A 2,4,6,N,N-pentamethylbenzamide preparation method INSIGHT HIGH TECHNOLOGY JIANGSU CO LTD 2015-11-04 CN disclosed
US-8778219-B2 Ionic liquids for separation of olefin-paraffin mixtures UT-BATTELLE, LLC (US) 2014-07-15 US disclosed
US-20130338389-A1 IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES UT-BATTELLE, LLC (US) 2013-12-19 US disclosed
US-8535560-B2 Ionic liquids for separation of olefin-paraffin mixtures UT-BATTELLE, LLC (US) 2013-09-17 US disclosed
US-20110015461-A1 Ionic Liquids for Separation of Olefin-Paraffin Mixtures UT-BATTELLE, LLC (US) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130338389-A1 IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES POU2F1, POU2F2, POF1B HPGD 3260/4885KMT2A 3578/4885SMN1; SMN2 1017/4885
US-12442027-B2 Method of reducing aromatic nitro compounds NNMT, CBR3, DHFR HPGD 169/4885KMT2A 718/4885SMN1; SMN2 1823/4885
US-12162816-B2 Method of reducing aromatic nitro compounds TYR, COMT, TH HPGD 1065/4885KMT2A 512/4885SMN1; SMN2 1477/4885
US-20110015461-A1 Ionic Liquids for Separation of Olefin-Paraffin Mixtures POU2F1, POU2F2, POF1B HPGD 3260/4885KMT2A 3578/4885SMN1; SMN2 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.