Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.46 |
| ▸ | TYK2 | P29597 | 9/20 | 0.36 |
| ▸ | JAK2 | O60674 | 8/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469593 | 0.95 | BTK (0.44) | BTKTYK2JAK2KDM1AKDR | |
| SCHEMBL1334382 | 0.77 | KDR (0.54) | KDR | |
| SCHEMBL12469189 | 0.77 | BTK (0.46) | BTKKDR | |
| SCHEMBL10048588 | 0.75 | BTK (0.44) | BTKKDR | |
| SCHEMBL12469765 | 0.75 | AURKA (0.40) | BTKKDR | |
| SCHEMBL12469516 | 0.75 | GRM2 (0.40) | BTKKDR | |
| SCHEMBL10049027 | 0.74 | PARP1 (0.35) | BTKTYK2JAK2KDR | |
| SCHEMBL12469667 | 0.73 | BTK (0.43) | BTK | |
| SCHEMBL12469427 | 0.73 | BTK (0.67) | BTKKDR | |
| SCHEMBL12469609 | 0.72 | BTK (0.39) | BTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |