Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469505 | 0.85 | BTK (0.41) | BTKKDRFLT3MAPK14 | |
| SCHEMBL12469562 | 0.83 | BTK (0.42) | BTKKDRFLT3 | |
| SCHEMBL12469481 | 0.82 | ALOX5 (0.40) | BTKKDRFLT3MAPK14 | |
| SCHEMBL12469765 | 0.82 | AURKA (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469508 | 0.80 | BTK (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469512 | 0.78 | CRBN (0.41) | BTK | |
| SCHEMBL12469573 | 0.77 | ALPL (0.40) | BTKKDRFLT3MAPK14 | |
| SCHEMBL12469038 | 0.77 | PARP1 (0.40) | BTKKDRMAPK14PARP1 | |
| SCHEMBL12469540 | 0.75 | L3MBTL1 (0.40) | BTKPARP1 | |
| SCHEMBL10049030 | 0.75 | BTK (0.46) | BTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |