Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 13/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469562 | 0.87 | BTK (0.42) | BTKKDRFLT3GRM2IKBKB | |
| SCHEMBL12469505 | 0.85 | BTK (0.41) | BTKKDRFLT3 | |
| SCHEMBL12469629 | 0.85 | KDR (0.41) | AURKABTKKDRGRM2IKBKB | |
| SCHEMBL12469508 | 0.84 | BTK (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469481 | 0.84 | ALOX5 (0.40) | BTKKDRFLT3 | |
| SCHEMBL12469512 | 0.84 | CRBN (0.41) | BTK | |
| SCHEMBL12469573 | 0.84 | ALPL (0.40) | BTKKDRFLT3 | |
| SCHEMBL1292654 | 0.83 | BTK (0.57) | AURKABTKKDRFLT3 | |
| SCHEMBL10048588 | 0.82 | BTK (0.44) | BTKKDRFLT3 | |
| SCHEMBL12469516 | 0.82 | GRM2 (0.40) | BTKKDRFLT3GRM2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |