SCHEMBL10049293

SCHEMBL10049293

FC(F)=Cc1cccc(F)c1-c1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.39
PDK2 Q15119 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
ERN1 O75460 1/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33
GRIN3A Q8TCU5 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14010604 0.79 NFE2L2 (0.45) NFE2L2PDK2CA1CA2CA7
SCHEMBL13615662 0.78 NFE2L2 (0.56) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30138202 0.78 NFE2L2 (0.56) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28859332 0.77 ERN1 (0.52) NFE2L2PDK2CA1CA2CA7
Ethyne SCHEMBL28542315 0.74 NFE2L2 (0.52) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13032947 0.72 NFE2L2 (0.39) NFE2L2MEN1KMT2AGRIN2DGRIN3B
SCHEMBL13439495 0.71 BACE1 (0.46) NFE2L2PDK2ERN1ALDH1A1MAPT
SCHEMBL24832675 0.71 ERN1 (0.39) NFE2L2ERN1ALDH1A1NPC1TRPA1
SCHEMBL10049291 0.70 PDK2 (0.35) PDK2CA1CA2CA7CA9
SCHEMBL28003673 0.70 MAOA (0.46) PDK2CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148006-B2 Electrolytic solution and battery SONY CORPORATION (JP) 2012-04-03 US disclosed
US-8148006-B2 Electrolytic solution and battery SONY CORPORATION (JP) 2012-04-03 US disclosed