SCHEMBL14010604

SCHEMBL14010604

F/C=C/c1cccc(F)c1-c1ccccc1F

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 11/20 0.45
PDK2 Q15119 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
ERN1 O75460 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049293 0.79 NFE2L2 (0.39) NFE2L2PDK2CA1CA2CA7
SCHEMBL28859332 0.78 ERN1 (0.52) NFE2L2PDK2CA1CA2CA7
SCHEMBL27541398 0.77 NFE2L2 (0.75) NFE2L2NPC1
SCHEMBL11672692 0.68 NFE2L2 (0.43) NFE2L2PDK2CA1CA2CA7
SCHEMBL31067193 0.67 PBRM1 (0.44) PDK2CA1CA2CA7CA9
SCHEMBL20618732 0.67 PDK2 (0.42) PDK2CA1CA2CA7CA9
SCHEMBL28003673 0.67 MAOA (0.46) PDK2CA1CA2CA7CA9
SCHEMBL30540277 0.67 PDK2 (0.42) PDK2CA1CA2CA7CA9
SCHEMBL8166983 0.67 GRIN2D (0.43) NFE2L2
SCHEMBL9181511 0.67 NFE2L2 (0.41) NFE2L2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080292970-A1 ELECTROLYTIC SOLUTION AND BATTERY SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080292970-A1 ELECTROLYTIC SOLUTION AND BATTERY SONY CORPORATION (JP) 2008-11-27 US disclosed