SCHEMBL13615662

SCHEMBL13615662

FC(F)=Cc1ccccc1F

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 9/20 0.56
TRPA1 O75762 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
GRIN2D O15399 2/20 0.45
GRIN3B O60391 2/20 0.45
GRIN1 Q05586 2/20 0.45
GRIN2A Q12879 2/20 0.45
GRIN2B Q13224 2/20 0.45
GRIN2C Q14957 2/20 0.45
GRIN3A Q8TCU5 2/20 0.45
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30138202 1.00 NFE2L2 (0.56) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
Ethyne SCHEMBL28542315 0.95 NFE2L2 (0.52) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL13032947 0.84 NFE2L2 (0.39) NFE2L2TRPA1GRIN2DGRIN3BGRIN1
SCHEMBL22721268 0.78 NFE2L2 (0.54) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL1475036 0.78 NFE2L2 (0.54) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL31147160 0.78 NFE2L2 (0.54) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL4518769 0.78 NFE2L2 (0.54) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL24832675 0.78 ERN1 (0.39) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL2822190 0.78 NFE2L2 (0.48) NFE2L2TRPA1CYP1A2CYP3A4CYP2C9
SCHEMBL10049293 0.78 NFE2L2 (0.39) NFE2L2TRPA1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12541047-B2 Optical film, polarizing plate comprising the same, and optical display apparatus comprising the same Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2026-02-03 US disclosed
EP-4628948-A1 POLARIZING PLATE AND OPTICAL DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2025-10-08 EP disclosed
EP-4621452-A1 POLARIZING PLATE AND OPTICAL DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2025-09-24 EP disclosed
US-20240241301-A1 POLARIZING PLATE AND OPTICAL DISPLAY APPARATUS Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2024-07-18 US disclosed
CN-118348630-A Polarizing plate and optical display device 三星SDI株式会社 2024-07-16 CN disclosed
WO-2024117660-A1 POLARIZING PLATE AND OPTICAL DISPLAY DEVICE 삼성에스디아이 주식회사 2024-06-06 WO disclosed
WO-2024106856-A1 POLARIZING PLATE AND OPTICAL DISPLAY DEVICE 삼성에스디아이 주식회사 2024-05-23 WO disclosed
CN-116360027-A Optical film, polarizing plate including the same, and optical display apparatus including the same 三星SDI株式会社 2023-06-30 CN disclosed
US-20230204823-A1 OPTICAL FILM, POLARIZING PLATE COMPRISING THE SAME, AND OPTICAL DISPLAY APPARATUS COMPRISING THE SAME Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2023-06-29 US disclosed
EP-2684859-B1 PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS UNIV OSAKA (JP) 2023-06-14 EP disclosed
EP-3042889-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN Asahi Glass Company, Limited (JP) 2016-07-13 EP disclosed
US-20160176791-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN ASAHI GLASS COMPANY, LIMITED (JP) 2016-06-23 US disclosed
CN-105517982-A Method for producing fluorine-containing olefin ASAHI GLASS CO LTD 2016-04-20 CN disclosed
US-9242911-B2 Preparation method for fluorine-containing olefins having organic-group substituents OSAKA UNIVERSITY (JP) 2016-01-26 US disclosed
US-9067200-B2 Method for producing substituted fluorine-containing olefin DAIKIN INDUSTRIES, LTD. (JP) 2015-06-30 US disclosed
EP-2684859-A1 PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS Osaka University (JP) 2014-01-15 EP disclosed
US-20130324757-A1 PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS DAIKIN INDUSTRIES (JP) 2013-12-05 US disclosed
EP-2543656-A1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN Daikin Industries, Ltd. (JP) 2013-01-09 EP disclosed
US-20120330072-A1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN OSAKA UNIVERSITY (JP) 2012-12-27 US disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120330072-A1 METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN FOS, POF1B, FOSB NFE2L2 166/4885TRPA1 3140/4885CYP1A2 1671/4885
US-20130324757-A1 PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS POF1B, OCIAD2, OGFOD1 NFE2L2 982/4885TRPA1 3245/4885CYP1A2 1653/4885
US-12541047-B2 Optical film, polarizing plate comprising the same, and optical display apparatus comprising the same MACF1, INCENP, SMCHD1 NFE2L2 745/4885TRPA1 426/4885CYP1A2 1295/4885
US-20160176791-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN FOS, CYP2F1, CYP4F11 NFE2L2 188/4885TRPA1 3904/4885CYP1A2 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.