SCHEMBL10049648

SCHEMBL10049648

Cc1ccc(C2(c3ccc(C)cc3)NC(=O)c3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 1/20 0.43
TNKS2 Q9H2K2 1/20 0.41
AKR1B1 P15121 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PGR P06401 1/20 0.39
CSNK1G1 Q9HCP0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GSK3B P49841 1/20 0.38
MAPT P10636 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20244137 0.90 ESR1 (0.39) ITGA4TNKS2AKR1B1MEN1KMT2A
SCHEMBL11990851 0.85 ITGA4 (0.48) ITGA4AKR1B1KDM4EALDH1A1HSD17B10
SCHEMBL18382550 0.84 AKR1B1 (0.40) AKR1B1MEN1KMT2AKDM4EALDH1A1
SCHEMBL10049655 0.83 KMT2A (0.50) ITGA4AKR1B1MEN1KMT2AKDM4E
SCHEMBL29508189 0.83 KMT2A (0.50) ITGA4AKR1B1MEN1KMT2AKDM4E
SCHEMBL22268171 0.82 TNKS2 (0.47) ITGA4TNKS2MEN1KMT2AKDM4E
SCHEMBL17814239 0.82 ATM (0.47) TNKS2AKR1B1MEN1KMT2APGR
SCHEMBL13668299 0.81 AGTR1 (0.45) ITGA4AKR1B1KMT2AKDM4EALDH1A1
SCHEMBL23212182 0.80 CA12 (0.53) ITGA4TNKS2AKR1B1PGRCSNK1G1
SCHEMBL17813126 0.80 ITGA4 (0.41) ITGA4AKR1B1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3448657-B1 LASER WELDABLE COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-22 EP disclosed
US-10456987-B2 Laser weldable compositions, articles formed therefrom, and methods of manufacture SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-29 US disclosed
US-20190169365-A1 POLY(ESTER-CARBONATE)S, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-06 US disclosed
US-20190134919-A1 LASER WELDABLE COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-05-09 US disclosed
US-20190127574-A1 POLY(ESTER-CARBONATE) COPOLYMERS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-05-02 US disclosed
EP-3353229-B1 POLY(ESTER-CARBONATE) COPOLYMERS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-01-30 EP disclosed
WO-2017187424-A1 POLY(ESTER-CARBONATE) COPOLYMERS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 WO disclosed
WO-2017187428-A1 LASER WELDABLE COMPOSITIONS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-11-02 WO disclosed
US-20120041102-A1 NOVEL EPOXY RESIN AND EPOXY RESIN COMPOSITION COMPRISING THE SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2012-02-16 US disclosed
US-20120041102-A1 NOVEL EPOXY RESIN AND EPOXY RESIN COMPOSITION COMPRISING THE SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2012-02-16 US disclosed