Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24160883 | 0.91 | MAPT (0.51) | ATMMAPTNPC1RAB9AHPGD | |
| SCHEMBL10049648 | 0.82 | ITGA4 (0.43) | TNKS2MAPTMAOAKMT2AAKR1B1 | |
| SCHEMBL29155428 | 0.82 | MAPT (0.50) | ATMMAPTNPC1RAB9AKMT2A | |
| SCHEMBL30683800 | 0.82 | MAPT (0.50) | ATMMAPTNPC1RAB9AKMT2A | |
| SCHEMBL11990851 | 0.81 | ITGA4 (0.48) | MAPTNPC1AKR1B1ALDH1A1CYP2C9 | |
| SCHEMBL18382550 | 0.80 | AKR1B1 (0.40) | MAPTNPC1RAB9ATP53HPGD | |
| SCHEMBL10049655 | 0.79 | KMT2A (0.50) | MAPTSMN1; SMN2TP53HPGDKMT2A | |
| SCHEMBL29508189 | 0.79 | KMT2A (0.50) | MAPTSMN1; SMN2TP53HPGDKMT2A | |
| SCHEMBL22268171 | 0.78 | TNKS2 (0.47) | TNKS2MAPTNPC1RAB9ATP53 | |
| SCHEMBL13668299 | 0.77 | AGTR1 (0.45) | MAPTSMN1; SMN2HPGDKMT2AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017005682-A1 | POLYCARBONATE COMPOSITIONS FOR GALVANIC APPLICATIONS HAVING A HIGH REQUIREMENT FOR HEAT DISTORTION POINT | COVESTRO DEUTSCHLAND AG (DE) | 2017-01-12 | — | — | WO | disclosed |
| WO-2017005677-A1 | GALVANIZED COMPONENT WITH HIGH HEAT DISTORTION RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2017-01-12 | — | — | WO | disclosed |
| WO-2016087480-A1 | COPOLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSING BEHAVIOUR CONTAINING PE-WAX | COVESTRO DEUTSCHLAND AG (DE) | 2016-06-09 | — | — | WO | disclosed |