Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 2/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | OGA | O60502 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18927291 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL25432185 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL14350660 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL9954647 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL28059299 | 0.86 | ALDH1A1 (0.33) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL23739250 | 0.86 | ALDH1A1 (0.33) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL5394485 | 0.78 | LGALS1 (0.36) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL4958591 | 0.78 | CA12 (0.37) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL24234938 | 0.78 | LGALS1 (0.36) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL19861525 | 0.78 | CA12 (0.37) | LGALS1LGALS3LGALS9LGALS8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093062-B2 | Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-10 | — | — | US | disclosed |
| US-20110118132-A1 | Enzymatic Assays Using Umbelliferone Substrates with Cyclodextrins in Droplets of Oil | ADVANCED LIQUID LOGIC, INC. (US) | 2011-05-19 | — | — | US | disclosed |