Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.32 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CDA | P32320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739250 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL14350660 | 0.86 | LGALS1 (0.39) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL9954647 | 0.86 | LGALS1 (0.39) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL10050864 | 0.86 | LGALS1 (0.39) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL25432185 | 0.86 | LGALS1 (0.39) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL18927291 | 0.86 | LGALS1 (0.39) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL13911679 | 0.78 | LGALS3 (0.40) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL13576871 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL14339418 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNATDP1LGALS1 | |
| SCHEMBL14998736 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TSHRLMNATDP1LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666856-B | Be directed to the purposes of double-stranded RNA compound in the medicine manufacturing treatment neuropathic pain of RhoA target gene | QUARK PHARMACEUTICALS, INC. (US) | 2016-04-06 | — | — | CN | disclosed |