Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 2/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | OGA | O60502 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18927291 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL25432185 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL10050864 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL14350660 | 1.00 | LGALS1 (0.39) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL28059299 | 0.86 | ALDH1A1 (0.33) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL23739250 | 0.86 | ALDH1A1 (0.33) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL5394485 | 0.78 | LGALS1 (0.36) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL4958591 | 0.78 | CA12 (0.37) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL24234938 | 0.78 | LGALS1 (0.36) | LGALS1LGALS3LGALS9LGALS8MEN1 | |
| SCHEMBL19861525 | 0.78 | CA12 (0.37) | LGALS1LGALS3LGALS9LGALS8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130315959-A1 | COMPOUNDS | NOVARTIS AG (CH) | 2013-11-28 | — | — | US | disclosed |
| EP-2655389-A2 | COMPOUNDS | Novartis AG (CH) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085668-A2 | COMPOUNDS | NOVARTIS AG (CH) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130315959-A1 | COMPOUNDS | DDOST, STT3B, KRTCAP2 | LGALS1 1698/4885LGALS3 1152/4885LGALS9 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.