Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381003 | 0.84 | MAPK1 (0.38) | MAPK1SMN1; SMN2ALDH1A1TSHRVDR | |
| SCHEMBL18651088 | 0.81 | MAPK1 (0.34) | MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23467006 | 0.78 | MAPK1 (0.43) | MAPK1SMN1; SMN2MGAMGAASI | |
| SCHEMBL20061753 | 0.78 | MAPK1 (0.43) | MAPK1SMN1; SMN2ALDH1A1VDRKDM4E | |
| Chloromethane SCHEMBL27511196 | 0.78 | GAA (0.52) | SMN1; SMN2MGAMGAASIMGAM2 | |
| SCHEMBL123093 | 0.77 | — | — | |
| SCHEMBL5579311 | 0.77 | ALDH1A1 (0.46) | MAPK1SMN1; SMN2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL18651063 | 0.77 | MAPK1 (0.42) | MAPK1SMN1; SMN2ALDH1A1VDRKDM4E | |
| SCHEMBL10019280 | 0.77 | MAPK1 (0.42) | MAPK1SMN1; SMN2ALDH1A1VDRHTT | |
| Ether SCHEMBL28452342 | 0.75 | GAA (0.55) | SMN1; SMN2MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324343-B2 | Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction | TOLMAR THERAPEUTICS, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120108511-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | QLT USA, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-20080194663-A1 | Sustained release inserts; mixture of thermoplastic polyester, solvent and leuprolide acetate; prostate cancer | QLT USA, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108511-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | PLG, PGF, PUF60 | MAPK1 3971/4885SMN1; SMN2 4215/4885MGAM 290/4885 |
| US-20080194663-A1 | Sustained release inserts; mixture of thermoplastic polyester, solvent and leuprolide acetate; prostate cancer | LPXN, GNRHR, AR | MAPK1 3574/4885SMN1; SMN2 1511/4885MGAM 728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.