Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541116 | 0.84 | MAPK1 (0.39) | MAPK1SMN1; SMN2ALDH1A1HTTVDR | |
| SCHEMBL11989017 | 0.80 | PAM (0.44) | MAPK1SMN1; SMN2 | |
| SCHEMBL20061753 | 0.80 | MAPK1 (0.43) | MAPK1SMN1; SMN2ALDH1A1HTTVDR | |
| SCHEMBL11989018 | 0.80 | MGAM (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL18651063 | 0.78 | MAPK1 (0.42) | MAPK1SMN1; SMN2ALDH1A1HTTVDR | |
| SCHEMBL5607319 | 0.77 | GAA (0.50) | ALDH1A1 | |
| SCHEMBL10051165 | 0.77 | MAPK1 (0.41) | MAPK1SMN1; SMN2ALDH1A1HTTVDR | |
| Hydrochloric Acid SCHEMBL23467006 | 0.76 | MAPK1 (0.43) | MAPK1SMN1; SMN2ALDH1A1HTTVDR | |
| SCHEMBL5514801 | 0.74 | NAAA (0.38) | ALDH1A1 | |
| SCHEMBL5579311 | 0.74 | ALDH1A1 (0.46) | MAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118881-A1 | NOVEL SUSTAINED RELEASE POLYMER | QLT USA, INC. | 2018-05-03 | — | — | US | disclosed |
| US-9914802-B2 | Sustained release polymer | TOLMAR THERAPEUTICS, INC. (US) | 2018-03-13 | — | — | US | disclosed |
| US-20170362377-A1 | NOVEL SUSTAINED RELEASE POLYMER | QLT USA, INC. | 2017-12-21 | — | — | US | disclosed |
| US-20170096524-A1 | NOVEL SUSTAINED RELEASE POLYMER | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2017-04-06 | — | — | US | disclosed |
| US-9539333-B2 | Sustained release polymer | TOLMAR THERAPEUTICS, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160220682-A1 | NOVEL SUSTAINED RELEASE POLYMER | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2016-08-04 | — | — | US | disclosed |
| US-9283282-B2 | Sustained release polymer | TOLMAR THERAPEUTICS, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140357574-A1 | NOVEL SUSTAINED RELEASE POLYMER | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2014-12-04 | — | — | US | disclosed |
| US-8840916-B2 | Sustained release polymer | TOLMAR THERAPEUTICS, INC. (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130303722-A1 | NOVEL SUSTAINED RELEASE POLYMER | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2013-11-14 | — | — | US | disclosed |
| US-8470359-B2 | Sustained release inserts; mixture of thermoplastic polyester, solvent and leuprolide acetate; prostate cancer | QLT USA, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8324343-B2 | Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction | TOLMAR THERAPEUTICS, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120108511-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | QLT USA, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-20090305957-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | QLT USA, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20080194663-A1 | Sustained release inserts; mixture of thermoplastic polyester, solvent and leuprolide acetate; prostate cancer | QLT USA, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108511-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | PLG, PGF, PUF60 | MAPK1 3971/4885SMN1; SMN2 4215/4885ALDH1A1 4270/4885 |
| US-20080194663-A1 | Sustained release inserts; mixture of thermoplastic polyester, solvent and leuprolide acetate; prostate cancer | LPXN, GNRHR, AR | MAPK1 3574/4885SMN1; SMN2 1511/4885ALDH1A1 910/4885 |
| US-20140357574-A1 | NOVEL SUSTAINED RELEASE POLYMER | LPXN, GNRHR, AR | MAPK1 3854/4885SMN1; SMN2 1484/4885ALDH1A1 1138/4885 |
| US-20170096524-A1 | NOVEL SUSTAINED RELEASE POLYMER | LPXN, GNRHR, AR | MAPK1 3854/4885SMN1; SMN2 1484/4885ALDH1A1 1138/4885 |
| US-20180118881-A1 | NOVEL SUSTAINED RELEASE POLYMER | LPXN, GNRHR, AR | MAPK1 3854/4885SMN1; SMN2 1484/4885ALDH1A1 1138/4885 |
| US-20090305957-A1 | PREPARATION OF BIODEGRADABLE POLYESTERS WITH LOW-BURST PROPERTIES BY SUPERCRITICAL FLUID EXTRACTION | PLG, PGF, PUF60 | MAPK1 3971/4885SMN1; SMN2 4215/4885ALDH1A1 4270/4885 |
| US-20170362377-A1 | NOVEL SUSTAINED RELEASE POLYMER | LPXN, GNRHR, AR | MAPK1 3854/4885SMN1; SMN2 1484/4885ALDH1A1 1138/4885 |
| US-20160220682-A1 | NOVEL SUSTAINED RELEASE POLYMER | LPXN, GNRHR, AR | MAPK1 3854/4885SMN1; SMN2 1484/4885ALDH1A1 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.