Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200201 | 0.79 | ALOX5 (0.53) | ALOX5MAOBMAOABCHECYP4F2 | |
| SCHEMBL10052009 | 0.76 | MAOB (0.43) | ALOX5MAOBMAOAGSTP1LMNA | |
| SCHEMBL557817 | 0.74 | LMNA (0.57) | ALOX5MAOBMAOABCHEGSTP1 | |
| SCHEMBL379281 | 0.72 | MAOB (0.67) | ALOX5MAOBMAOABCHEGSTP1 | |
| SCHEMBL2137838 | 0.71 | MRGPRX4 (0.69) | ALOX5MAOBMAOABCHEGSTP1 | |
| SCHEMBL6756098 | 0.70 | RAB9A (0.46) | MAOAKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL3371655 | 0.70 | ALOX5 (0.61) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL1041386 | 0.70 | ALOX5 (0.61) | ALOX5MAOBMAOALMNACYP1A2 | |
| SCHEMBL1268719 | 0.69 | MAOB (0.81) | ALOX5MAOBMAOABCHECYP4F2 | |
| SCHEMBL4674930 | 0.69 | MEN1 (0.70) | ALOX5MAOBMAOABCHEGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019299-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |