Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745554 | 0.88 | BCHE (0.58) | BCHEACHEALDH1A1CHKALMNA | |
| SCHEMBL10137263 | 0.86 | BCHE (0.39) | BCHEACHECHKA | |
| SCHEMBL26497813 | 0.82 | ACHE (0.53) | BCHEACHEALDH1A1TRPA1TSHR | |
| SCHEMBL22422901 | 0.76 | ACHE (0.63) | BCHEACHEALDH1A1CHKALMNA | |
| Hydrochloric Acid SCHEMBL21328515 | 0.74 | ACHE (0.61) | BCHEACHEALDH1A1CHKALMNA | |
| SCHEMBL10325407 | 0.72 | ACHE (0.64) | BCHEACHEALDH1A1CHKALMNA | |
| SCHEMBL331501 | 0.71 | TRPA1 (0.47) | ALDH1A1TRPA1TSHR | |
| Hydrochloric Acid SCHEMBL11637202 | 0.70 | ACHE (0.61) | BCHEACHEALDH1A1CHKALMNA | |
| SCHEMBL93665 | 0.70 | CHKA (0.59) | BCHEACHEALDH1A1CHKALMNA | |
| Bromide SCHEMBL2831425 | 0.70 | ACHE (0.68) | BCHEACHEALDH1A1CHKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905118-B2 | Triscationic amphiphile compounds, compositions, and methods for making same | JAMES MADISON INNOVATIONS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20170135342-A1 | NOVEL TRISCATIONIC AMPHIPHILE COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING SAME | JAMES MADISON UNIVERSITY | 2017-05-18 | — | — | US | disclosed |
| US-20170135342-A1 | NOVEL TRISCATIONIC AMPHIPHILE COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING SAME | JAMES MADISON UNIVERSITY | 2017-05-18 | — | — | US | disclosed |
| US-8980925-B2 | Antimicrobial amphiphiles and methods for their use | JAMES MADISON INNOVATIONS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980925-B2 | Antimicrobial amphiphiles and methods for their use | JAMES MADISON INNOVATIONS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140148487-A1 | ANTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | James Madison Innovations, Inc, (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140148487-A1 | ANTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | James Madison Innovations, Inc, (US) | 2014-05-29 | — | — | US | disclosed |
| WO-2012054695-A1 | NTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | JAMES MADISON INNOVATIONS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170135342-A1 | NOVEL TRISCATIONIC AMPHIPHILE COMPOUNDS, COMPOSITIONS, AND METHODS FOR MAKING SAME | PHOSPHO1, ABHD16A, SMPD1 | BCHE 1459/4885ACHE 2000/4885ALDH1A1 3358/4885 |
| US-10905118-B2 | Triscationic amphiphile compounds, compositions, and methods for making same | PHOSPHO1, POLR1C, ABHD16A | BCHE 1446/4885ACHE 2084/4885ALDH1A1 3071/4885 |
| US-20140148487-A1 | ANTIMICROBIAL AMPHIPHILES AND METHODS FOR THEIR USE | ANXA5, ANXA4, ANXA6 | BCHE 1688/4885ACHE 3208/4885ALDH1A1 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.