Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.74 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.52 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346925 | 0.86 | PTGS2 (0.80) | PTGS2SENP5SENP2SENP1NMT1 | |
| SCHEMBL347478 | 0.86 | PTGS2 (1.00) | PTGS2SENP5SENP2SENP1NMT1 | |
| SCHEMBL347919 | 0.81 | PTGS2 (0.76) | PTGS2SENP5SENP2SENP1NMT1 | |
| SCHEMBL10021087 | 0.79 | PTGS2 (0.72) | PTGS2SENP5SENP2SENP1NMT1 | |
| SCHEMBL347428 | 0.75 | PTGS2 (0.70) | PTGS2 | |
| SCHEMBL19876777 | 0.75 | ALDH1A1 (0.44) | PTGS2SENP5SENP2SENP1PPARA | |
| SCHEMBL347207 | 0.74 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL2634030 | 0.74 | MAPK14 (0.76) | MAPK14LSSPPARAMAOANAMPT | |
| SCHEMBL10481490 | 0.74 | MAPK14 (0.56) | PTGS2MAPK14SENP5SENP2SENP1 | |
| SCHEMBL1623348 | 0.73 | PTGS2 (0.67) | PTGS2SENP5SENP2SENP1NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | PTGER2, PTGES2, PTGIR | PTGS2 4/4885MAPK14 2056/4885SENP5 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.