Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347478 | 0.82 | PTGS2 (1.00) | PTGS2MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10021087 | 0.81 | PTGS2 (0.72) | PTGS2MAPTALDH1A1TP53HPGD | |
| SCHEMBL346925 | 0.78 | PTGS2 (0.80) | PTGS2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL347919 | 0.76 | PTGS2 (0.76) | PTGS2MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10052333 | 0.75 | PTGS2 (0.74) | PTGS2 | |
| SCHEMBL1623348 | 0.75 | PTGS2 (0.67) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL347207 | 0.74 | PTGS2 (1.00) | PTGS2CA2MAPTALDH1A1HPGD | |
| SCHEMBL3817884 | 0.73 | CA2 (0.70) | CHRNB2CHRNA4CA2MAPTMEN1 | |
| SCHEMBL6570852 | 0.72 | CA2 (0.69) | CHRNB2CHRNA4CA2MAPTMEN1 | |
| SCHEMBL22323341 | 0.72 | MEN1 (0.66) | CHRNB2CHRNA4BCHECA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | claimed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | claimed |
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | disclosed |
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | PTGER2, PTGES2, PTGIR | PTGS2 4/4885MCL1 2051/4885CHRNB2 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.