SCHEMBL10053148

SCHEMBL10053148

COc1cccc(B2OCc3cc(F)ccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
PDE3A Q14432 1/20 0.46
PDE4A P27815 4/20 0.39
PDE4B Q07343 4/20 0.39
PDE4C Q08493 4/20 0.39
PDE4D Q08499 4/20 0.39
NFE2L2 Q16236 2/20 0.38
MAOB P27338 2/20 0.37
PTGS1 P23219 1/20 0.36
CBX7 O95931 1/20 0.35
CDYL2 Q8N8U2 1/20 0.35
CDYL Q9Y232 1/20 0.35
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
NPY5R Q15761 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053159 0.85 CA1 (0.49) CA1CA2PDE3APDE4APDE4B
SCHEMBL500789 0.84 CA1 (0.54) CA1CA2PDE3APDE4APDE4B
SCHEMBL500011 0.82 CA1 (0.49) CA1CA2PDE3APDE4APDE4B
SCHEMBL10053155 0.82 CA1 (0.46) CA1CA2PDE3APDE4APDE4B
SCHEMBL10076823 0.80 CA1 (0.47) CA1CA2PDE3APDE4APDE4B
SCHEMBL10053167 0.80 CA1 (0.47) CA1CA2PDE3APDE4APDE4B
SCHEMBL10053150 0.80 CA1 (0.47) CA1CA2PDE3APDE4APDE4B
SCHEMBL500219 0.80 CA1 (0.56) CA1CA2PDE3APDE4APDE4B
SCHEMBL500064 0.80 CA1 (0.49) CA1CA2PDE3APDE4APDE4B
SCHEMBL10053207 0.79 PDE4B (0.50) PDE3APDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2024-06-27 US disclosed
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2024-06-27 US disclosed
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2023-10-03 US disclosed
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2023-10-03 US disclosed
US-20220361503-A1 LARGE-SCALE METHODS OF UNIFORMLY COATING PACKAGING SURFACES WITH A VOLATILE ANTIMICROBIAL TO PRESERVE FOOD FRESHNESS ALTER DOMUS US LLC 2022-11-17 US disclosed
US-11202448-B2 Volatile applications against pathogens AGROFRESH INC. (US) 2021-12-21 US disclosed
EP-3148551-B1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2021-09-29 EP disclosed
US-11039617-B2 Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2021-06-22 US disclosed
US-20200296967-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS ALTER DOMUS US LLC 2020-09-24 US disclosed
US-20200296966-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS AGROFRESH INC (US) 2020-09-24 US disclosed
US-20140349853-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-11-27 US disclosed
US-20140349853-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-11-27 US disclosed
WO-2014120715-A2 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-08-07 WO disclosed
US-20140221312-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-08-07 US disclosed
US-20140221312-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS DOW AGROSCIENCES LLC (US) 2014-08-07 US disclosed
US-8106031-B2 Hydrolytically-resistant boron-containing therapeutics and methods of use ANACOR PHARMACEUTICALS, INC. (US) 2012-01-31 US disclosed
US-8106031-B2 Hydrolytically-resistant boron-containing therapeutics and methods of use ANACOR PHARMACEUTICALS, INC. (US) 2012-01-31 US disclosed
WO-2007131072-A2 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE ANACOR PHARMACEUTICALS, INC. (US) 2007-11-15 WO disclosed
US-20070265226-A1 Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use ANACOR PHARMACEUTICALS (US) 2007-11-15 US disclosed
US-20070265226-A1 Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use ANACOR PHARMACEUTICALS (US) 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11202448-B2 Volatile applications against pathogens OXA1L, VAPB, TIAL1 CA1 3741/4885CA2 3017/4885PDE3A 3288/4885
US-20140349853-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS OXA1L, BROX, BOLA2; BOLA2B CA1 4683/4885CA2 3828/4885PDE3A 2610/4885
US-20240206470-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS OXA1L, VAPB, TIAL1 CA1 3741/4885CA2 3017/4885PDE3A 3288/4885
US-20140221312-A1 USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS OXA1L, BROX, BOLA2; BOLA2B CA1 4683/4885CA2 3828/4885PDE3A 2610/4885
US-11039617-B2 Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness FOSB, TAS2R10, TMBIM6 CA1 3842/4885CA2 3591/4885PDE3A 2017/4885
US-20200296966-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS OXA1L, VAPB, TIAL1 CA1 3741/4885CA2 3017/4885PDE3A 3288/4885
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness TAS2R10, FOSB, TMBIM6 CA1 3929/4885CA2 3745/4885PDE3A 2224/4885
US-20200296967-A1 VOLATILE APPLICATIONS AGAINST PATHOGENS OXA1L, VAPB, TIAL1 CA1 3741/4885CA2 3017/4885PDE3A 3288/4885
US-20070265226-A1 Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use GAA, BTD, MANBA CA1 838/4885CA2 535/4885PDE3A 3530/4885
US-20220361503-A1 LARGE-SCALE METHODS OF UNIFORMLY COATING PACKAGING SURFACES WITH A VOLATILE ANTIMICROBIAL TO PRESERVE FOOD FRESHNESS TAS2R10, FOSB, TMBIM6 CA1 3929/4885CA2 3745/4885PDE3A 2224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.