SCHEMBL1005334

SCHEMBL1005334

[CH2]Cc1ccccc1CCl

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.34
IDO1 P14902 2/20 0.33
PNMT P11086 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HSPA5 P11021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150237 0.85 TSHR (0.50) ALDH1A1TSHRKMT2AIDO1PNMT
SCHEMBL132297 0.85 HSPA5 (0.38) TSHRIDO1PNMTTAAR1HSPA5
SCHEMBL29350459 0.85 TSHR (0.50) ALDH1A1TSHRKMT2AIDO1PNMT
Ammonia Solution, Strong SCHEMBL30821298 0.82 TSHR (0.48) ALDH1A1TSHRKMT2AIDO1PNMT
Hydrochloric Acid SCHEMBL9192215 0.82 TSHR (0.48) ALDH1A1TSHRKMT2AIDO1PNMT
Ammonia Solution, Strong SCHEMBL29017600 0.82 TSHR (0.48) ALDH1A1TSHRKMT2AIDO1PNMT
SCHEMBL8660782 0.79 ALDH1A1 (0.39) ALDH1A1TSHRKMT2AIDO1PNMT
SCHEMBL8550582 0.77 HSPA5 (0.46) ALDH1A1TSHRKMT2AIDO1PNMT
SCHEMBL6654438 0.72 IDO1 (0.50) IDO1HSPA5
SCHEMBL7865281 0.72 PNMT (0.56) ALDH1A1TSHRPNMTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104448868-B A kind of SBS modified pitch based on graphene oxide and preparation method thereof 山西省交通科学研究院 2017-07-07 CN claimed
EP-0857770-B1 Coating compositions, hydrophilic films, and hydrophilic film-coated articles SHINETSU CHEMICAL CO (JP) 2004-09-22 EP claimed
US-6114440-A EMULSION POLYMERIZING AN AQUEOUS SOLUTION OF A WATER-INSOLUBLE GROUP-BEARING SILICONE RESIN AND A VINYL SILANETRIOL MONOMER; COATED AND CURED INTO A FILM HAVING WEAR AND CHEMICAL RESISTANCE AND WATERPROOFING PROPERTIES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-09-05 US claimed
US-5973068-A BLEND OF WATER INSOLUBLE SILICONE RESIN AND VINYL MONOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-10-26 US claimed
CN-108264744-A A kind of environment-friendly degradable plastics 湖州科博信息科技有限公司 2018-07-10 CN disclosed
EP-3194471-A1 POLYSILOXANE CO-OR TERPOLYMERS AND POLYMERS MADE THEREFROM Momentive Performance Materials Inc. (US) 2017-07-26 EP disclosed
US-20160200878-A1 Branched additives for polymer toughening THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2016-07-14 US disclosed
WO-2016044695-A1 POLYSILOXANE CO-OR TERPOLYMERS AND POLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-03-24 WO disclosed
US-9181432-B2 Branched additives for polymer toughening THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2015-11-10 US disclosed
EP-0841355-B1 Silicone resin-containing emulsion compositions, methods for making them, and cured films thereof SHINETSU CHEMICAL CO (JP) 2015-08-26 EP disclosed
US-20130303712-A1 BRANCHED ADDITIVES FOR POLYMER TOUGHENING THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-11-14 US disclosed
EP-0932083-B1 Coating composition for electrifying members and electrophotographic carrier SHINETSU CHEMICAL CO (JP) 2012-09-05 EP disclosed
EP-0932083-A2 Coating composition for electrifying members and electrophotographic carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-07-28 EP disclosed
US-5844060-A Organopolysiloxane resin, production method thereof, and curable organopolysiloxane resin composition using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-01 US disclosed
EP-0857770-A2 Coating compositions, hydrophilic films, and hydrophilic film-coated articles SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-08-12 EP disclosed
EP-0841355-A2 Silicone resin-containing emulsion compositions, methods for making them, and cured films thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-05-13 EP disclosed
EP-0624262-B1 METHOD OF APPLYING A LACQUER FILM SENSITIVE TO UV AND/OR ELECTRON-BEAM RADIATION FRAUNHOFER GES FORSCHUNG (DE) 1998-05-06 EP disclosed
EP-0752441-A2 Organopolysiloxane resin, production method thereof, and curable organopolysiloxane resin composition using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-01-08 EP disclosed
US-5506008-A Method of applying a lacquer film sensitive to ultraviolet and/or electron radiation FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1996-04-09 US disclosed
WO-1992008758-A1 SILICONE SURFACE-MODIFIED AMMONIUM POLYPHOSPHATE PPG INDUSTRIES, INC. (US) 1992-05-29 WO disclosed