SCHEMBL6654438

SCHEMBL6654438

[CH2]Cc1ccccc1CS

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.50
DCLRE1A Q6PJP8 1/20 0.31
DCLRE1B Q9H816 1/20 0.31
FOLH1 Q04609 1/20 0.31
HSPA5 P11021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132297 0.85 HSPA5 (0.38) IDO1HSPA5
SCHEMBL125429 0.85 IDO1 (0.63) IDO1DCLRE1ADCLRE1BFOLH1HSPA5
SCHEMBL29365799 0.85 IDO1 (0.63) IDO1DCLRE1ADCLRE1BFOLH1HSPA5
SCHEMBL3074785 0.72 PNMT (0.50) IDO1
SCHEMBL6073331 0.72 IDO1 (0.50) IDO1DCLRE1ADCLRE1BFOLH1HSPA5
SCHEMBL839232 0.72 GABRA1 (0.46)
SCHEMBL27791324 0.72 TRPA1 (0.39) IDO1HSPA5
SCHEMBL6632824 0.72 APOBEC3G (0.48) HSPA5
SCHEMBL1005334 0.72 ALDH1A1 (0.41) IDO1HSPA5
SCHEMBL9168805 0.72 IDO1 (0.50) IDO1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759457-B2 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2004-06-16 EP claimed
EP-0759457-B1 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2001-06-13 EP claimed
US-5814703-A ORGANIC RESIN AND SILICONE COMPOUND; PROTECTIVE COATINGS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-09-29 US claimed
EP-0759457-A2 Weather and soiling-resistant silicone-containing coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-02-26 EP claimed
EP-1462496-A2 Coating composition and method for application thereof KANSAI PAINT CO., LTD. (JP) 2004-09-29 EP disclosed
EP-0759457-B2 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2004-06-16 EP disclosed
US-6319557-B1 FORMING MULTILAYER OVERCOATING, COLORING, THERMOSETTING RESIN FILMS, EPOXY ACRYLIC RESINS AND CATALYST KANSAI PAINT CO., LTD. (JP) 2001-11-20 US disclosed
US-6262147-B1 AS TOP COATS TO AUTOMOBILES KANSAI PAINT CO., LTD. (JP) 2001-07-17 US disclosed
EP-0759457-B1 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6015848-A CURABLE MIXTURE OF ALICYCLIC EPOXY COMPOUND, EPOXY GROUP-CONTAINING ACRYLIC RESIN, CATIONIC POLYMERIZATION CATALYST, AND FLUOROPOLYMER KANSAI PAINT CO., LTD. (JP) 2000-01-18 US disclosed
US-5902847-A COMPOSITION PREPARED BY MIXING ORGANIC SOLVENT BASED COATING WITH SILICONE POLYMER HAVING ORGANOFUNCTIONAL GROUP AND HYDROLYZABLE GROUP IN ONE MOLECULE KANSAI PAINT CO., LTD. (JP) 1999-05-11 US disclosed
US-5814703-A ORGANIC RESIN AND SILICONE COMPOUND; PROTECTIVE COATINGS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-09-29 US disclosed
EP-0846739-A2 Coating composition and method for application thereof KANSAI PAINT CO., LTD. (JP) 1998-06-10 EP disclosed
EP-0759457-A2 Weather and soiling-resistant silicone-containing coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-02-26 EP disclosed