SCHEMBL10053399

SCHEMBL10053399

CN1C(=O)c2ccc(S(=O)(=O)c3ccc4c(c3)C(=O)N(C)C4=O)cc2C1=O

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
HSD17B10 Q99714 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALOX15 P16050 1/20 0.49
CASP3 P42574 1/20 0.48
APP P05067 7/20 0.47
HPGD P15428 2/20 0.47
MAPK1 P28482 1/20 0.47
POLB P06746 3/20 0.47
KDM4E B2RXH2 2/20 0.42
PTGS2 P35354 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773011 0.93 ALDH1A1 (0.70) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL12963170 0.90 ALDH1A1 (0.62) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL14678930 0.88 ALDH1A1 (0.61) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL10451373 0.88 ALDH1A1 (0.65) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL14125085 0.84 CA9 (0.62) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL21795325 0.84 ALDH1A1 (0.55) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL19759273 0.82 ALDH1A1 (0.54) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL19634570 0.79 ALDH1A1 (0.51) ALDH1A1MEN1MAPTKMT2AL3MBTL1
SCHEMBL14005760 0.78 CA9 (0.54) ALDH1A1MEN1MAPTKMT2AHSD17B10
SCHEMBL13256767 0.78 ALDH1A1 (0.53) ALDH1A1APPPOLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9835965-B2 Charge control agent and toner using same HODOGAYA CHEMICAL CO., LTD. (JP) 2017-12-05 US disclosed
US-20170333836-A1 GAS SEPARATION ASYMMETRIC MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, AND GAS SEPARATION METHOD FUJIFILM CORPORATION (JP) 2017-11-23 US disclosed
US-20160216628-A1 Charge Control Agent and Toner Using Same HODOGAYA CHEMICAL CO., LTD. (JP) 2016-07-28 US disclosed
US-8586700-B2 Method for preparing a poly(ether sulfonimide or -amide) copolymer using cyclic oligomers KOREA REASEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2013-11-19 US disclosed
US-20130053530-A1 METHOD FOR PREPARING A POLY(ETHER SULFONIMIDE OR -AMIDE) COPOLYMER USING CYCLIC OLIGOMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2013-02-28 US disclosed
US-20130053530-A1 METHOD FOR PREPARING A POLY(ETHER SULFONIMIDE OR -AMIDE) COPOLYMER USING CYCLIC OLIGOMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2013-02-28 US disclosed
US-8202674-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2012-06-19 US disclosed
US-8202674-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2012-06-19 US disclosed
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2011-02-03 US disclosed
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2011-02-03 US disclosed
US-7651744-B2 Liquid crystal display INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-01-26 US disclosed
US-20090234092-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2009-09-17 US disclosed
US-20090234092-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2009-09-17 US disclosed
US-7544450-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2009-06-09 US disclosed
US-7544450-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2009-06-09 US disclosed
US-7449268-B2 Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements XEROX CORPORATION (US) 2008-11-11 US disclosed
US-7449268-B2 Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements XEROX CORPORATION (US) 2008-11-11 US disclosed
US-20080171275-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2008-07-17 US disclosed
US-20080171275-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2008-07-17 US disclosed
US-20070087134-A1 Includes a color filter substrate and an array substrate, wherein at least one of the color filter substrate and the array substrate comprises a polyimide; can be directly filmed on a glass substrate; haze-free INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028724-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS SLC43A3, SLC29A1, SLCO1A2 ALDH1A1 884/4885MEN1 2326/4885MAPT 318/4885
US-20130053530-A1 METHOD FOR PREPARING A POLY(ETHER SULFONIMIDE OR -AMIDE) COPOLYMER USING CYCLIC OLIGOMERS PFAS, PUF60, PPIP5K2 ALDH1A1 4871/4885MEN1 1184/4885MAPT 2854/4885
US-20160216628-A1 Charge Control Agent and Toner Using Same PHF8, CECR2, ASH2L ALDH1A1 4757/4885MEN1 769/4885MAPT 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.