Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078717 | 0.95 | SLC2A1 (0.33) | SLC2A1ALDH1A1POLBKMT2ANPSR1 | |
| SCHEMBL10055405 | 0.87 | RAB9A (0.32) | ALDH1A1RAB9AKDM4EMEN1POLB | |
| SCHEMBL10055481 | 0.84 | RAB9A (0.32) | RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10055476 | 0.84 | KMT2A (0.43) | ALDH1A1RAB9AKDM4EMEN1POLB | |
| SCHEMBL725109 | 0.82 | MAPT (0.33) | MAPT | |
| SCHEMBL10078718 | 0.78 | EGFR (0.31) | MAPT | |
| SCHEMBL724879 | 0.78 | MAPT (0.38) | ALDH1A1RAB9AKDM4EMEN1POLB | |
| SCHEMBL16491074 | 0.74 | PLA2G2A (0.43) | ALDH1A1RAB9AKDM4EMEN1POLB | |
| SCHEMBL16491036 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EMEN1POLBKMT2A | |
| SCHEMBL19578975 | 0.73 | ELANE (0.37) | ALDH1A1RAB9AKDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702001-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150307933-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
| US-8906612-B2 | Scaffold-based polymerase enzyme substrates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120077189-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077189-A1 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | POLM, RNGTT, POLR1G | SLC2A1 4856/4885ALDH1A1 1906/4885RAB9A 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.