Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056056 | 0.88 | MEN1 (0.45) | MEN1KMT2AEPHX2PPARGCA1 | |
| SCHEMBL10055187 | 0.85 | L3MBTL1 (0.44) | ATML3MBTL1MEN1KMT2APKM | |
| SCHEMBL10056203 | 0.79 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2TSHRNPC1 | |
| SCHEMBL10055215 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2APKMSMN1; SMN2NPC1 | |
| SCHEMBL10055235 | 0.76 | PPID (0.45) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15044032 | 0.75 | SMN1; SMN2 (0.42) | MEN1KMT2APKMSMN1; SMN2NPC1 | |
| SCHEMBL10055319 | 0.75 | CYP2C9 (0.48) | L3MBTL1MEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL10056291 | 0.75 | TSHR (0.56) | L3MBTL1MEN1KMT2ACA7CA14 | |
| SCHEMBL10055797 | 0.75 | CARM1 (0.47) | L3MBTL1MEN1KMT2AEPHX2PKM | |
| SCHEMBL10056343 | 0.74 | PPID (0.43) | SMN1; SMN2NPC1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |