Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056387 | 0.90 | CARM1 (0.47) | CARM1PRMT6ALDH1A1NPC1RAB9A | |
| SCHEMBL10055187 | 0.89 | L3MBTL1 (0.44) | CARM1PRMT6ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL10055319 | 0.88 | CYP2C9 (0.48) | CARM1PRMT6ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10056291 | 0.88 | TSHR (0.56) | CARM1PRMT6LMNAMEN1KMT2A | |
| SCHEMBL10055215 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL10055489 | 0.75 | CYP2C9 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10055475 | 0.75 | ATM (0.42) | ALDH1A1NPC1SMN1; SMN2PKMLMNA | |
| SCHEMBL9201083 | 0.73 | CARM1 (0.69) | CARM1PRMT6ALDH1A1NPC1RAB9A | |
| SCHEMBL10936984 | 0.72 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL4588187 | 0.72 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |