Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055489 | 0.82 | CYP2C9 (0.50) | L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL10055215 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL10056387 | 0.71 | CARM1 (0.47) | SMN1; SMN2 | |
| SCHEMBL10055319 | 0.71 | CYP2C9 (0.48) | MAPK1L3MBTL1CYP1A2CYP2D6MAPT | |
| SCHEMBL30791568 | 0.70 | PTK2 (0.53) | WDR5MAOBMAPK1L3MBTL1 | |
| SCHEMBL10056326 | 0.69 | ALDH1A1 (0.37) | MAPK1P2RX3MAPTTSHRSMN1; SMN2 | |
| SCHEMBL15044016 | 0.67 | — | — | |
| SCHEMBL18080787 | 0.66 | L3MBTL1 (0.45) | MAOBMAPK1L3MBTL1P2RX3MAPT | |
| Hydrochloric Acid SCHEMBL25217806 | 0.65 | CYP1A2 (0.46) | CYP1A2KMO | |
| SCHEMBL26459530 | 0.64 | WDR5 (0.42) | WDR5MAOBMAPK1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |