Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055215 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10055489 | 0.83 | CYP2C9 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL10056387 | 0.81 | CARM1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2CARM1 | |
| SCHEMBL10056291 | 0.74 | TSHR (0.56) | MEN1KMT2AMAPK1TSHRMAPT | |
| SCHEMBL10057054 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10055187 | 0.72 | L3MBTL1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL10055797 | 0.71 | CARM1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL10055319 | 0.71 | CYP2C9 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL10056056 | 0.70 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL10057071 | 0.69 | WDR5 (0.37) | SMN1; SMN2MAPK1TSHRMAPTP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |