SCHEMBL10059282

SCHEMBL10059282

c1ccc2cc(-c3nc(-c4ccc5ccccc5c4)nc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccc7c8ccccc8c8ccccc8c67)ccc54)n3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38
TUBB6 Q9BUF5 1/20 0.38
TUBB2B Q9BVA1 1/20 0.38
TUBB1 Q9H4B7 1/20 0.38
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
AKT1 P31749 1/20 0.32
PTGES O14684 1/20 0.31
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10059039 0.92 ALDH1A1 (0.32) ALDH1A1NPY5R
SCHEMBL10059264 0.91 TUBB4A (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059127 0.90 TUBB4A (0.42) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059931 0.89 ALDH1A1 (0.35) PTGESALDH1A1HPGDNPY5R
SCHEMBL16812254 0.87 TUBB4A (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059285 0.87 TUBB4A (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059272 0.86 TUBB4A (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059105 0.86 ALDH1A1 (0.35) ALDH1A1CYP1A2HPGDHSD17B10CYP11B1
SCHEMBL23156635 0.84 ALDH1A1 (0.35) PTGESALDH1A1HPGDNPY5R
SCHEMBL10059266 0.84 TDP1 (0.37) PTGESALDH1A1CYP1A2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 US disclosed
US-11316113-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-04-26 US disclosed
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-14 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
WO-2012023947-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885
US-11316113-B2 Organic electroluminescent materials and devices TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.