SCHEMBL10059264

SCHEMBL10059264

c1ccc2cc(-c3nc(-c4ccc5ccccc5c4)nc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccc7ccccc67)ccc54)n3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39
TUBB8 Q3ZCM7 1/20 0.39
TUBA3E Q6PEY2 1/20 0.39
TUBA1A Q71U36 1/20 0.39
TUBA1C Q9BQE3 1/20 0.39
TUBB6 Q9BUF5 1/20 0.39
TUBB2B Q9BVA1 1/20 0.39
TUBB1 Q9H4B7 1/20 0.39
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16812254 0.96 TUBB4A (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059266 0.91 TDP1 (0.37) TDP1ALDH1A1GAAMAPTSMN1; SMN2
SCHEMBL10059282 0.91 TUBB4A (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059029 0.90 ALDH1A1 (0.35) TDP1ALDH1A1MAPTSMN1; SMN2L3MBTL1
SCHEMBL20988555 0.90 TUBB4A (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL10059056 0.89 TUBB4A (0.43) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15197757 0.89 TSPO (0.36) TDP1ALDH1A1MAPTSMN1; SMN2L3MBTL1
SCHEMBL10130188 0.88 ESR1 (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23183722 0.88 TUBB4A (0.35) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23183896 0.88 TUBB4A (0.35) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 US disclosed
US-11316113-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-04-26 US disclosed
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-03-14 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-9954180-B2 Bicarbazole compounds for OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2018-04-24 US disclosed
US-9831439-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-9831439-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20170170409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-15 US disclosed
US-20150171335-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171335-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20140131665-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
US-20130140549-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-06-06 US disclosed
WO-2012023947-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885
US-11316113-B2 Organic electroluminescent materials and devices TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885
US-20190081246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYMS, UMPS, TYMP TUBB4A 1241/4885TUBB 746/4885TUBA3C 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.