SCHEMBL10060036

SCHEMBL10060036

OC[C@H]1OC(n2ccc3c(Cl)ncnc32)[C@@H](F)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 1/20 0.55
▸ SLC29A1 Q99808 1/20 0.53
▸ ADK P55263 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1689454 1.00 METTL3 (0.55) METTL3SLC29A1ADK
SCHEMBL1689451 1.00 METTL3 (0.55) METTL3SLC29A1ADK
SCHEMBL15948784 1.00 METTL3 (0.55) METTL3SLC29A1ADK
SCHEMBL10079496 1.00 METTL3 (0.55) METTL3SLC29A1ADK
SCHEMBL14429079 0.95 SLC29A1 (0.54) SLC29A1ADK
SCHEMBL14429029 0.95 SLC29A1 (0.54) SLC29A1ADK
SCHEMBL1689438 0.90 METTL3 (0.52) METTL3SLC29A1ADK
SCHEMBL1689441 0.90 METTL3 (0.52) METTL3SLC29A1ADK
SCHEMBL13005628 0.89 ADK (0.64) METTL3SLC29A1ADK
SCHEMBL1797344 0.89 ADK (0.64) METTL3SLC29A1ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120010164-A1 ANTIVIRAL AGENTS SURNMA VINCENZO (IT) 2012-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010164-A1 ANTIVIRAL AGENTS EIF2AK2, HAVCR2, MAVS METTL3 2422/4885SLC29A1 59/4885ADK 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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