Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 4/20 | 0.52 |
| ▸ | ADK | P55263 | 3/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689441 | 1.00 | METTL3 (0.52) | METTL3ADKPRMT5WDR77SLC29A1 | |
| SCHEMBL10060036 | 0.90 | METTL3 (0.55) | METTL3ADKSLC29A1 | |
| SCHEMBL1689454 | 0.90 | METTL3 (0.55) | METTL3ADKSLC29A1 | |
| SCHEMBL1689451 | 0.90 | METTL3 (0.55) | METTL3ADKSLC29A1 | |
| SCHEMBL10079496 | 0.90 | METTL3 (0.55) | METTL3ADKSLC29A1 | |
| SCHEMBL15948784 | 0.90 | METTL3 (0.55) | METTL3ADKSLC29A1 | |
| SCHEMBL31228131 | 0.90 | ADK (0.59) | METTL3ADKPRMT5WDR77SLC29A1 | |
| SCHEMBL14429029 | 0.85 | SLC29A1 (0.54) | ADKSLC29A1 | |
| SCHEMBL14429079 | 0.85 | SLC29A1 (0.54) | ADKSLC29A1 | |
| SCHEMBL1797344 | 0.79 | ADK (0.64) | METTL3ADKSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596005-A2 | ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2013-05-29 | — | — | EP | disclosed |
| US-20120010164-A1 | ANTIVIRAL AGENTS | SURNMA VINCENZO (IT) | 2012-01-12 | — | — | US | disclosed |
| WO-2010084115-A2 | ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010164-A1 | ANTIVIRAL AGENTS | EIF2AK2, HAVCR2, MAVS | METTL3 2422/4885ADK 2649/4885PRMT5 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.