Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106421 | 0.96 | THRB (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10060078 | 0.88 | THRB (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10079190 | 0.87 | THRB (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10093557 | 0.86 | TSHR (0.40) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10060076 | 0.86 | THRB (0.44) | THRBTSHRALDH1A1 | |
| SCHEMBL10060075 | 0.83 | THRB (0.42) | THRBTSHR | |
| SCHEMBL23031228 | 0.82 | THRB (0.38) | THRBTSHR | |
| SCHEMBL23031325 | 0.81 | TSHR (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL10093547 | 0.81 | TSHR (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10067755 | 0.81 | TSHR (0.37) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| EP-2578200-B1 | Compounds for infiltrating and/or sealing of dental hard substance and method | VOCO GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2436365-B1 | Composite material comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2017-03-08 | — | — | EP | disclosed |
| EP-2436366-B1 | Composite material comprising a monomer with a polyalicyclic structure as sealing material | VOCO GMBH (DE) | 2015-07-29 | — | — | EP | disclosed |
| US-9079828-B2 | Polymerizable compounds comprising a polyalicylic structure element | VOCO GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-9079828-B2 | Polymerizable compounds comprising a polyalicylic structure element | VOCO GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-9023916-B2 | Composite material comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-9023916-B2 | Composite material comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-8979535-B2 | Compositions for infiltration and/or sealing of hard tooth tissue and corresponding methods | VOCO GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-8979535-B2 | Compositions for infiltration and/or sealing of hard tooth tissue and corresponding methods | VOCO GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082958-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082958-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| US-20120082954-A1 | Composition Comprising a Monomer with a Polyalicyclic Structure Element for Filling and/or Sealing a Root Canal | VOCO GMBH (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-2436668-A1 | Polymerisable compounds comprising a polyalicyclic structure element | VOCO GmbH (DE) | 2012-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082958-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element | INTS9, PARG, SMCHD1 | THRB 4587/4885TSHR 4846/4885ALDH1A1 1183/4885 |
| US-20120082959-A1 | Polymerizable Compounds Comprising a Polyalicylic Structure Element | PCBP1, PUF60, PARG | THRB 4037/4885TSHR 4695/4885ALDH1A1 3882/4885 |
| US-20120082637-A1 | Lacquer Composition Comprising a Monomer with a Polyalicyclic Structure Element | PELP1, ERCC1, GLRA1 | THRB 2532/4885TSHR 1595/4885ALDH1A1 4274/4885 |
| US-20120083550-A1 | Composite Material Comprising a Monomer with a Polyalicyclic Structure Element as a Sealing Material | ERCC1, PARG, EPN1 | THRB 4507/4885TSHR 4875/4885ALDH1A1 1710/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | THRB 4522/4885TSHR 4596/4885ALDH1A1 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.