Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919927 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL13700490 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL21987044 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL15759448 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL21987047 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL20919929 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL2584632 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL21987045 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL14384743 | 0.83 | KMT2A (0.58) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A | |
| SCHEMBL761891 | 0.83 | KMT2A (0.58) | ALDH1A1TDP1SMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307553-B1 | Modified splenopentines, their process of preparation and their use | BERLIN CHEMIE AG (DE) | 1994-06-15 | — | — | EP | claimed |
| WO-2024130535-A1 | ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE | 东莞新能源科技有限公司 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024130537-A1 | ELECTROLYTE, ELECTROCHEMICAL APPARATUS AND ELECTRONIC APPARATUS | 东莞新能源科技有限公司 | 2024-06-27 | — | — | WO | disclosed |
| US-9242921-B2 | Process for producing aromatic carboxylic acid | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2016-01-26 | — | — | US | disclosed |
| EP-2081955-B1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-8765909-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8404643-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-7960348-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20110118172-A1 | METASTIN DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110059888-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-10 | — | — | US | disclosed |
| US-4948534-A | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0326106-A2 | Alkylene diamines | Takeda Chemical Industries, Ltd. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0127098-B1 | DERIVATIVES OF BETA-AMINO-GAMMA-TRIMETHYLAMMONIO-BUTYRATE, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| US-4767781-A | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-08-30 | — | — | US | disclosed |
| EP-0127098-A2 | Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-05 | — | — | EP | disclosed |
| US-4105608-A | HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT | SHOWA DENKO K.K. (JP) | 1978-08-08 | — | — | US | disclosed |
| US-4059561-A | AND A HALOGEN COMPOUND | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4022954-A | ADHESIVES, FLOCCULATING AGENTS, ION EXCHANGE RESINS, MOLDING AGENTS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-05-10 | — | — | US | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |
| US-3959234-A | CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059888-A1 | METASTIN DERIVATIVES AND USE THEREOF | SHBG, GNRHR, INHA | ALDH1A1 3927/4885TDP1 4653/4885SMN1; SMN2 2768/4885 |
| US-20110118172-A1 | METASTIN DERIVATIVE AND USE THEREOF | GNRHR, SHBG, INHA | ALDH1A1 3515/4885TDP1 4668/4885SMN1; SMN2 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.