Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21987047 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL21987045 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL20919927 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL13700490 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL21987044 | 0.87 | ALDH1A1 (0.57) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL2584632 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL1006031 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL4274070 | 0.82 | MAPK1 (0.53) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7183170 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7178769 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174615-A1 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2024-05-30 | — | — | US | disclosed |
| EP-4320101-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20230074115-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | Cipla USA, Inc. | 2023-03-09 | — | — | US | disclosed |
| WO-2022216900-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |
| US-20200317652-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | Cipla USA, Inc. | 2020-10-08 | — | — | US | disclosed |
| CN-111655709-A | Synthesis of antibacterial aminoglycoside analogs | 轩竹(北京)医药科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| EP-3697797-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | Cipla USA, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019079613-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317652-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | MRPL21, SPOUT1, AARS1 | ALDH1A1 3668/4885TDP1 2893/4885SMN1; SMN2 4634/4885 |
| US-20230074115-A1 | SYNTHESIS OF ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | MRPL21, SPOUT1, AARS1 | ALDH1A1 3668/4885TDP1 2893/4885SMN1; SMN2 4634/4885 |
| US-20240174615-A1 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | MLST8, MTOR, RICTOR | ALDH1A1 4721/4885TDP1 2289/4885SMN1; SMN2 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.