Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642128 | 0.89 | CLK4 (0.55) | CHRNA7CLK4MAPTKDM4ETP53 | |
| SCHEMBL10060648 | 0.82 | GRM5 (0.47) | NPC1RAB9ANPSR1KCNH2MEN1 | |
| SCHEMBL10060646 | 0.80 | L3MBTL1 (0.61) | APPMAPTKDM4ETP53NPC1 | |
| SCHEMBL274985 | 0.78 | APP (0.45) | APPMCHR1CHRNA7CLK4MAPT | |
| SCHEMBL338452 | 0.77 | CLK4 (0.64) | APPCLK4MAPTKDM4ETP53 | |
| SCHEMBL674764 | 0.77 | APP (0.77) | APPMCHR1MAPTKDM4ENPC1 | |
| SCHEMBL10300057 | 0.77 | APP (0.77) | APPMCHR1MAPTKDM4ENPC1 | |
| SCHEMBL2876553 | 0.75 | CLK4 (0.61) | CLK4MAPTKDM4ETP53NPC1 | |
| SCHEMBL15896952 | 0.75 | CLK4 (0.61) | CLK4MAPTKDM4ETP53NPC1 | |
| SCHEMBL26793564 | 0.75 | CHRNA7 (0.49) | CHRNA7CLK4MAPTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120082836-A1 | RESIN COMPOSITION FOR LASER ENGRAVING, RESIN PRINTING PLATE PRECURSOR FOR LASER ENGRAVING, RELIEF PRINTING PLATE AND METHOD FOR PRODUCTION OF RELIEF PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2012-04-05 | — | — | US | disclosed |